Agenda: Protein Arginine Methylation

Agenda

Conference Organizers:

Rong Huang, PhD, Professor of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN

Jian Xu, PhD, Associate Professor of Dentistry, University of Southern California, Los Angeles, CA

Schedule is subject to change. Each speaker will present their talk live. The presentations' recordings will be accessible to registered attendees after the sessions, contingent upon speakers who have granted permission..

Day 1 Agenda: Biology

Time (Eastern)	Event
11:00 am—11:10 am	FASEB Welcome & Organizer Welcome
Session 1	Moderator: Frankie Yang, City of Hope, Los Angeles, CA
11:10 am—11:40 am	Keynote Lecture Identifying a New Effector Protein for SDMA Marks on GAR Motifs Mark Bedford, PhD, Professor, University of Texas MD Anderson Cancer Center, Houston, TX
11:40 am—12:00 pm	Epigenetic PRMT7 Regulation Promotes Extravasation of Monocytes Thomas M. Conlon, Team Leader Research Group Immunopathology of COPD, LHI, Institute of Lung Health and Immunity, Munich, Germany
12:00 pm—12:20 pm	The Arginine Methyltransferase PRMT5, a Regulator of the Activity of Steroid Receptor in Breast Cancer Coralie Poulard, Centre de Recherche en Cancérologie de Lyon, Lyon, France
12:20 pm—12:40 pm	Protein Arginine Methylation in Cancer Cell Signaling Wenjian Gan, PhD, Associate Professor, Medical University of South Carolina, Charleston, SC
12:40 pm—1:10 pm	Keynote Lecture Mechanisms of PRMT5-dependent Gene Expression Regulation David Shechter, PhD, Professor, Albert Einstein College of Medicine, Bronx, NY
1:10 pm—1:25 pm	Break
Session 2	Moderator: Pengda Liu, University of North Carolina, Chapel Hill, NC
1:25 pm—1:55 pm	Keynote Lecture The Dedicated Function of PRMT9 in RNA Splicing Yanzhong Yang, PhD, Associate Professor, Department of Cancer Genetics and Epigenetics, City of Hope
1:55 pm—2:15 pm	CARM1-mediated Skeletal Muscle Plasticity Vladimir Ljubicic, PhD, Associate Professor, McMaster University, Hamilton, Canada
2:15 pm—2:35 pm	A New Function of PRMT5 in the Mitochondria Shihuan Kuang, PhD, Professor of animal sciences, Purdue University, West Lafayette, IN
2:35 pm—2:50 pm	PRMT1-regulated Intron Retention Controls ECM Expression During Craniofacial Development Julia Lima, MS, Research Assistant, University of Southern California, Los Angeles, CA
2:50 pm—3:20 pm	Keynote Lecture CARM1 Is a Therapeutic Vulnerability in Breast Cancer Wei Xu, Marian A. Messerschmidt Professor of Oncology, University of Wisconsin-Madison, Madison, WI

Day 2: Therapeutics

Time (Eastern)	Event
11:00 am—11:10 am	Organizer Recap Day 1 & Kickoff Day 2
Session 1	Moderator: N.I. (Nathaniel) Martin, Institute of Biology Leiden (IBL), Leiden University, Leiden, The Netherlands
11:10 am—11:40 am	Keynote Lecture The Long and Winding Road: Discovering and Validating Protein Arginine Methyltransferase Inhibitors Gianluca Sbardella, PhD, Professor of Medicinal Chemistry, Università di Salerno, Baronissi, Italy
11:40 am—12:00 pm	Regulation of PRMT1 Activity by Oligomerization Joan Hevel, PhD, Associate Professor in Biochemistry, Utah State University, Salt Lake City, UT
12:00 pm—12:20 pm	AntiDOTes for Diseases: Chemistry and Biology Match Together to Tackle Epigenetics Paola Barbara Arimondo, PhD, Institut Pasteur, Paris, France
12:20 pm—12:50 pm	Keynote Lecture Targeting the Arginine Methylation Binder SMNDC1 Stefan Kubicek, Professor, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
12:50 pm—1:05 pm	Break
Session 2	Moderator: Minkui Luo, Memorial Sloan Kettering Cancer Center, New York, NY
1:05 pm—1:25 pm	Chemical Probe to Investigate PRMT9 Function in Myeloid Cells Dalia Barsyte-Lovejoy, MSc, PhD, Assistant Professor, University of Toronto, Toronto, Canada
1:25 pm—1:45 pm	Mechanism and Impact of PRMT1-PRMT6 Interaction George Zheng, PhD, Panoz Professor of Pharmacy, University of Georgia, Athens, GA
1:45 pm—2:05 pm	Venturing into the Discovery of New Potential PRMT Inhibitors Akshay Kulkarni, PhD, Postdoctoral Scholar, Purdue University, West Lafayette, IN
2:05 pm—2:35 pm	Keynote Lecture Discovery of MTA Cooperative PRMT5 Inhibitor Ho-man Chan, PhD, Head of Epigenetics, Research & Development, AstraZeneca
2:35 pm—2:40 pm	Organizers' Closing Remarks