Celebrating DNA Day 2025 with FASEB Publications

In recognition of National DNA Day 2025, The FASEB Journal and FASEB BioAdvances present a collection of articles highlighting recent advances in DNA research across biological and biomedical sciences. National DNA Day, observed each year on April 25, marks both the completion of the Human Genome Project in 2003 and the discovery of the double helix in 1953—two milestones that continue to shape modern science. Led by the National Human Genome Research Institute (NHGRI), DNA Day is a global effort to foster discovery, collaboration, and innovation in genomics. Reflecting the scope and mission of FASEB's journals, this collection features high quality, peer reviewed studies spanning DNA methylation and epigenetics, inflammation and immune response, and cell death and apoptosis. We invite researchers to explore this selection and engage with the latest findings that are driving the future of genomic science.

*Note: Articles in this collection may be freely accessible, published under an open access license, or available only through subscription. If your institution provides access, you can read subscription-only articles in full. Otherwise, you can recommend the journal to your institution’s librarian.

PCSK9 causes inflammation and cGAS/STING pathway activation in diabetic nephropathy
Zhicai Feng, et al.
The FASEB Journal, 10 August 2023

Gasdermins mediate cellular release of mitochondrial DNA during pyroptosis and apoptosis
Carlos de Torre-Minguela, et al.
The FASEB Journal, 07 July 2021

Aerobic exercise training resets the human skeletal muscle methylome 10 years after breast cancer treatment and survival
Piotr P. Gorski, et al.
The FASEB Journal, 21 December 2022

The cGAS-STING pathway: The role of self-DNA sensing in inflammatory lung disease
Ruihua Ma, et al.
The FASEB Journal, 28 August 2020

Mitigating the detrimental developmental impact of early fetal alcohol exposure using a maternal methyl donor-enriched diet
Mélanie Breton-Larrivée, et al.
The FASEB Journal, 01 March 2023

Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2
Yunzhen Ye, et al.
The FASEB Journal, 10 October 2018

Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training
Macsue Jacques, et al.
The FASEB Journal, 12 September 2023

Liquid-liquid phase separation and fibrillation of the prion protein modulated by a high-affinity DNA aptamer
Carolina O. Matos, et al.
The FASEB Journal, 22 November 2019

Glutathione safeguards TET-dependent DNA demethylation and is critical for the acquisition of totipotency and pluripotency during preimplantation development
Juan Liu, et al.
The FASEB Journal, 06 February 2024

Melanin distribution in human epidermis affords localized protection against DNA photodamage and concurs with skin cancer incidence difference in extreme phototypes
Damilola Fajuyigbe, et al.
The FASEB Journal, 02 February 2018

Liver-specific deletion of de novo DNA methyltransferases protects against glucose intolerance in high-fat diet-fed male mice
S. Yao, et al.
The FASEB Journal, 25 May 2024

NF-κB p65 dimerization and DNA-binding is important for inflammatory gene expression
Tabea Riedlinger, et al.
The FASEB Journal, 07 December 2018

DNA hypomethylation of Syk induces oxidative stress and apoptosis via the PKCβ/P66shc signaling pathway in diabetic kidney disease
Rui Zhang, et al.
The FASEB Journal, 24 March 2024

LncRNA Dnmt3aos regulates Dnmt3a expression leading to aberrant DNA methylation in macrophage polarization
Xueqin Li, et al.
The FASEB Journal, 13 February 2020

Reduced rDNA transcription diminishes skeletal muscle ribosomal capacity and protein synthesis in cancer cachexia
Hyo-Gun Kim, et al.
The FASEB Journal, 02 February 2021

Tumor gene therapy by systemic delivery of plasmid DNA with cell-penetrating peptides
Kadri Künnapuu, et al.
FASEB BioAdvances, 23 October 2018