Biomechanical and Biochemical Impact of Collagens in Cancer

March 23 - 24, 2022

Summary

March 23-24, 2022

Our understanding of intratumoral collagen function is rapidly evolving. It has become clear that individual collagens can have unique pro-and anti-tumor roles in various contexts. The purpose of this catalyst conference is to bring together experts in these emerging areas to establish collaborations and formulate strategies for addressing critical questions including, but not limited to, collagen as a 1) signaling molecule 2) a physical substrate 4) a mediator of intratumoral physical forces 5) a mediator of metastasis and 6) the role of tumor-specific collagen post-translational modifications. The ultimate goal of the meeting is to encourage the development of these ideas and establish the utility of tumor collagens as biomarkers and therapeutic targets in cancer.

Organizers

T.S. Karin Eisinger, PhD

Ann B. Young Assistant Professor, Department of Pathology and Laboratory Medicine,Assistant Investigator, Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Penn Sarcoma Program