This FASEB SRC will bring together international scientists from different backgrounds to discuss cutting-edge developments in the areas of immunoreceptors and immunotherapy. Immunoreceptors encompass an array of receptor types, including B/T cell receptors, cytokine and immunomodulatory receptors that play a central role in cancer, autoimmunity and infectious disease. Although the field of immunoreceptors is well established, there are significant growth areas that continue to drive the field forward. An important aspect of this SRC is that it encompasses the development of state-of-the-art approaches ranging from molecular biophysics (e.g. single molecule imaging) to humanized mouse models to investigate multiple facets of immunoreceptor behavior.
Given the multiple recent advances in the area of cytokines and their receptors, and the relevance of this to immune responses, this topic is a new addition to the program for the 2018 meeting. In addition, immunomodulatory receptors have become key mediators and targets for immunotherapy. Immunotherapy represents one of the most rapidly expanding areas in cancer therapy and will also be included. This SRC will provide a highly interactive and collaborative environment for scientists to discuss ideas and develop new interactions. We expect that attendees from multiple backgrounds (e.g. immunologists, cell biologists, structural biologists, microscopists, translational scientists) will benefit from this meeting. Given the relevance of immunoreceptors to therapy, we also anticipate that attendees from both biopharma and academia will attend.
The meeting format is designed to facilitate the active participation of students and post-doctoral fellows. In addition to recreational activities and meet-the-expert sessions, the poster sessions provide a forum for scientific interchange between junior and senior investigators. Around 16 short talks will also be selected from poster abstracts, providing many opportunities for trainees/early-stage investigators to present their research orally.