GTPases in Trafficking, Autophagy and Disease

Conference Summary

Arf, Arl, Rab and Rag GTPases control traffic, proteostasis, membrane dynamics, signaling and lipid metabolism.  Intensive investigation of the cellular, molecular and structural mechanisms has led to surprising discoveries and paradigm shifts such as non-classical interactions and modifications controlling localization and function.  New fields have emerged (e.g. Rag GTPases in proteostasis), and dis-regulation of small GTPase networks has been implicated in human disease conditions from inherited disorders to complex disease states.

This SRC brings together investigators interested in trafficking regulation, membrane dynamics, proteostasis, and disease etiology for a focused meeting titled, "GTPases in Trafficking, Autophagy and Disease".  Represented disciplines will include biochemists, structural biologists, membrane biologists, cell biologists, geneticists, bioinformaticists, systems biologists, developmental biologists, neurobiologists, microbiologists, cancer biologists, virologists, immunologists, and others.  This exceptional diversity reflects the fundamental role of trafficking GTPases in biological processes and disease.  There will be ten sessions on topics such as Activation and deactivation of GTPases, Regulation of and by post translational modifications, Structural and molecular mechanisms, Small GTPases in the endocytic system, Small GTPases in the secretory system, Small GTPases in membrane trafficking in specialized cells, Autophagy, Rag GTPases, and GTPases and disease. The sessions will include 30 regular talks and at least 12 short talks selected from abstracts.  The opening session will include an Overview of the evolution of trafficking GTPases followed by 2 min preview talks by poster presenters.  In addition to talks and poster sessions, recreational activities will provide opportunities for students, postdoctoral fellows, new investigators and established leaders to interact and explore collaborative possibilities.

View the Program Agenda

Important Deadlines:   Early Bird: August 4, 2016         Last Day to Register: August 18, 2016


  • Meet the experts session
  • Short talks selected from abstracts and 2 min poster preview talks
  • Sunday welcome reception

Keynote Speakers

Anne Ridley with the talk entitled Rho GTPases, cell migration and cancer

Conference Organizers

David Lambright
UMASS Medical School

Antonella De Matteis
Telethon Institute of Genetics and Medicine, Italy 

Conference Staff

Kristen Hagy, CMP, Conference Manager 
Pippa O'Shea, Conference Assistant

Contact us:
Email:  src@faseb.org   Phone: 1.301.634.7010

Date & Location

Date: September 18-23, 2016
Location: Marriott West Palm Beach
                 1001 Okeechobee Boulevard
                 West Palm Beach, FL

Transportation & Lodging

Airport Information

Palm Beach International Airport (PBI) is less than 3 miles from the West Palm Beach Marriott.  Fort Lauderdale airport (FLL) is one hour away.

West Palm Beach Marriott Complimentary Airport Shuttle service to/from the airport is available. Use the courtesy phone located in the baggage claim area to contact the hotel for transfer to the hotel.  Shuttle hours are 6 a.m. - midnight.  

Click the links below for Transportation & Lodging information

Official Conference Lodging

Marriott West Palm Beach
1001 Okeechobee Boulevard
West Palm Beach, FL

If you request a single or a double occupancy room, the registration fee covers 5 nights of lodging (Sunday through Thursday night, checkout Friday morning). A credit card will be required upon check-in for incidental expenses (i.e. in-room movies, room service, etc.)

If you plan to arrive early or stay beyond the conference dates, please contact Alice Fay at the Marriott at alice.fay@marriott.com. You are responsible for payment upon check-out.

Click here for additional Offsite Lodging.